A model-driven approach to industrializing discovery processes in pharmaceutical research

ion, mappings between adjacent layers, and an implementation of this hierarchy using information technology-level execution elements. This approach is applied to the assay development phase of the drug discovery process. First, a business operations model is built by identifying the business artifacts, developing models for the life cycles of these artifacts, and then creating a comprehensive model that combines these life-cycle models and their interactions. Using the concept of adaptive business objects, a solution composition model that expands on the business operations model is developed. This model is then mapped into an executable platform-specific implementation by using the IBM WebSpheret platform. Our prototype system was built and validated as a joint effort between IBM Research and